WP4 – Natural products and medicinal plants
The final goal of workpackage 4 is to find new extracts, natural products or natural product inspired synthetic compounds improving the health span of humans. First step is to test thousands of compounds and extracts on health span enhancement in C. elegans to get a deeper insight into the mechanisms of ageing. The focus will be put on compounds derived from edible and medicinal plants. Compounds with proven activity in C. elegans will be further investigated in mice. Preclinical development may be performed with promising candidates to prepare all necessary data for clinical trials subsequently after finishing this project.